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Showing content with the highest reputation on 31/12/20 in all areas

  1. If life is a journey, I want my money back from the operator.
    2 points
  2. It's the latter. All those numbers are estimates based on what we’ve seen with the interval between doses in the two-dose studies. No studies have been specifically done on efficacy of a single dose; not for Pfizer/BioNTech, not for Moderna, not for AstraZeneca/Oxford. However, that limited trial data suggests moderate to high efficacy after a single dose; the main issue seems to be lack of data on how long does the immunity last, whether it fades away much faster without the second booster dose, and whether a longer delay between the two doses is significantly detrimental for long-term immunity. More data would be nice, but either way, the limited data we do have seems to suggest that a single dose is enough to prevent severe cases and significantly reduce hospitalisations for weeks (longest interval between the two doses was 26 weeks in the AZ/Oxford trials), which is pretty encouraging. The only vaccine that has trialed a one-dose protocol is the Johnson & Johnson one, the data should be available any time now, and they are also running an additional two-dose protocol trials, so that should be very useful in providing a direct comparison of a single vs multiple dose regimens.
    1 point
  3. I don't think many people can even come close to Dylan but this perhaps tops it, without wanting to sound pretentious it's incredibly moving
    1 point
  4. Onto the next Murakami book I go.
    1 point
  5. Hello, is it me you're looking for?
    1 point
  6. I read somewhere they're changing strategy to get as many people 1 dose as possible and then worry about the second afterwards, rather than making sure everyone who gets one dose also gets the second in 28 days. Makes sense as there was evidence that one dose gets you some level of resistance to the virus, but I wonder if there's a maximum time limit in which you have to get the second dose for it to work. For instance I got an injection for something (I want to say yellow fever but could be wrong) where it gave me 2 years immunity but if I got a booster within six months it would be permanent.
    0 points
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